Key result
Progression of valvar aortic stenosis occurred at a mean rate of 6.5 mmHg per year, which was significantly faster in patients with baseline valve calcification or regurgitation (P<0.02).
Population
65 patients with valvar aortic stenosis who had been investigated by cardiac catheterization on at least two…
Design
Cohort
Follow-up
mean 7 years (range 1-17 years)
Authors
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Patients with baseline calcification or regurgitation warrant closer AS surveillance; hypothesis-generating for intervention timing in this cohort.
Cohort (n=65)
p-value: p=<0.02
Aortic stenosis progresses at a mean rate of 6.5 mmHg per year, with faster progression in those with baseline calcification or regurgitation, suggesting early intervention may be warranted during concomitant cardiac surgery.
Davies et al. (1991) conducted a cohort in valvar aortic stenosis (n=65). Progression of valvar aortic stenosis occurred at a mean rate of 6.5 mmHg per year, which was significantly faster in patients with baseline valve calcification or regurgitation (P<0.02).
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