Key result
Aortic stiffness, measured by pulse wave velocity, is an independent predictor of cardiovascular morbidity and mortality and increases in the presence of advanced aortic calcification.
Population
Humans (general population discussed in the context of arterial stiffness and cardiovascular disease)
Design
Review
Authors
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PWV may refine CV risk stratification in observational cohorts with calcification; leaves open whether targeting stiffness improves outcomes in trials.
This review highlights that aortic stiffness, measured by pulse wave velocity, is a key independent predictor of cardiovascular events driven primarily by age, blood pressure, and advanced calcification rather than early atherosclerosis.
Cecelja et al. (2012) conducted a review in Cardiovascular disease. Pulse wave velocity (PWV) was evaluated. Aortic stiffness, measured by pulse wave velocity, is an independent predictor of cardiovascular morbidity and mortality and increases in the presence of advanced aortic calcification.
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