Key result
Integrative treatment with Jiangya Capsule and nimodipine was superior to either treatment alone in decreasing systolic blood pressure in elderly patients with isolated systolic hypertension (P<0.05).
Why the study?
Does integrative treatment (Jiangya Capsule plus nimodipine) or TCM (Jiangya Capsule) improve blood pressure and vasoactive biomarkers compared to nimodipine alone in elderly patients with isolated systolic hypertension?
Population
270 elderly patients with isolated systolic hypertension (ISH) from Beijing, China.
Comparison
Integrative treatment or Traditional Chinese… vs Western medicine for 4 weeks.
Design
RCT, randomly divided into 3 groups, double-blind
Follow-up
4 weeks
Authors
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Supports Jiangya Capsule plus nimodipine over monotherapy for elderly isolated systolic hypertension; extends evidence for integrative TCM-Western regimens.
RCT (n=270)
Double-blind
randomized
Yes
Does integrative treatment (Jiangya Capsule plus nimodipine) or TCM (Jiangya Capsule) improve blood pressure and vasoactive biomarkers compared to nimodipine alone in elderly patients with isolated systolic hypertension?
p-value: p=<0.05
Integrative treatment combining Jiangya Capsule and nimodipine was superior to either treatment alone in reducing systolic blood pressure in elderly patients with isolated systolic hypertension.
H. Li (2010) conducted an RCT in isolated systolic hypertension (ISH) (n=270). Integrative treatment (Jiangya Capsule plus nimodipine) or TCM treatment (Jiangya Capsule) vs. Western medicine (nimodipine plus Jiangya Capsule simulation) was evaluated on office blood pressure, 24-hour ambulatory blood pressure, and vasoactive agents (p=<0.05). Integrative treatment with Jiangya Capsule and nimodipine was superior to either treatment alone in decreasing systolic blood pressure in elderly patients with isolated systolic hypertension (P<0.05).
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