Key result
4D flow MRI demonstrated that left heart flow patterns differ by age and gender, with young individuals having more LA diastolic vortices than older individuals (1.6 vs. 0.7, P=0.01).
Why the study?
Do age, gender, blood pressure, and ventricular geometry influence normal 3D blood flow characteristics in the left heart measured by 4D flow MRI in healthy volunteers?
Population
24 healthy volunteers divided into two age groups: <30 years (n=12, 6 women) and >50 years (n=12, 6 women).
Comparison
4D flow magnetic resonance imaging (MRI) vs Comparison between age groups and gender
Design
Cross-sectional
Authors
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Age/gender differences in normal left heart flow on 4D flow MRI support age-specific references; leaves open clinical relevance in disease.
Cross-Sectional (n=24)
Do age, gender, blood pressure, and ventricular geometry influence normal 3D blood flow characteristics in the left heart measured by 4D flow MRI in healthy volunteers?
Absolute Event Rate: 1.6% vs 0.7%
p-value: p=0.01
Normal 3D blood flow patterns in the left heart assessed by 4D flow MRI demonstrate significant differences related to age, gender, blood pressure, and ventricular geometry.
Föll et al. (2012) conducted a cross-sectional in Healthy volunteers (n=24). 4D flow MRI vs. Age and gender groups was evaluated on Number of diastolic vortices in the left atrium (p=0.01). 4D flow MRI demonstrated that left heart flow patterns differ by age and gender, with young individuals having more LA diastolic vortices than older individuals (1.6 vs. 0.7, P=0.01).
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