Key result
Right ventricular hypertrophy is linked to ~twofold higher flow wave amplitude at the right coronary inlet.
Why the study?
Does right ventricular hypertrophy alter the shape of normalized flow and wall shear stress waves in the right coronary arterial tree compared to control?
Population
Control and right ventricular hypertrophy (RVH) hearts
Comparison
Right ventricular hypertrophy (RVH) condition vs Control hearts
Design
Preclinical
Authors
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RVH inlet flow changes should not yet inform practice; leaves open whether stiffness preserves distal wave shape in humans.
Does right ventricular hypertrophy alter the shape of normalized flow and wall shear stress waves in the right coronary arterial tree compared to control?
p-value: p=> 0.05
In right ventricular hypertrophy, coronary blood flow is increased at the inlet but the shape of normalized flow and wall shear stress waves is preserved throughout the arterial tree due to increased stiffness.
Huo et al. (2018) studied Right ventricular hypertrophy. Right ventricular hypertrophy vs. Control was evaluated on Mean and amplitude of flow waves at the inlet of the right coronary arterial tree and precapillary arterioles (p=> 0.05). Right ventricular hypertrophy was associated with a twofold increase in flow wave amplitude at the right coronary arterial tree inlet versus controls, with no difference in precapillary arterioles.
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