Key result
Plasma amylin concentrations were significantly increased in hypertensive individuals (P=0.027) and in normotensive individuals with a family history of hypertension (P<0.001).
Why the study?
Is circulating amylin increased in prehypertensive individuals and those with essential hypertension?
Observational (n=283)
Is circulating amylin increased in prehypertensive individuals and those with essential hypertension?
p-value: p=0.027
Circulating amylin is elevated in essential hypertension and in normotensive individuals with a family history of hypertension, suggesting it may serve as a hereditary intermediate phenotype.
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Elevated amylin may mark hereditary hypertension risk; cross-sectional data leave causal and clinical roles open.
Kailasam et al. (2000) conducted an observational in Essential hypertension (n=283). Plasma amylin concentrations were significantly increased in hypertensive individuals (P=0.027) and in normotensive individuals with a family history of hypertension (P<0.001).
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