February 1, 2003Journal of Biomechanical Engineering
A New Automated Method for the Quantification of Mitral Regurgitant Volume and Dynamic Regurgitant Orifice Area based on a Normalized Centerline Velocity Distribution using Color M-mode and Continuous Wave Doppler Imaging
Key result
A new automated model for estimating mitral regurgitant orifice diameter and volume showed close agreement with reference values in an in vitro flow model (r=0.96 and r=0.93, respectively).
Population
Computational fluid dynamics simulations and experimental data from an in vitro flow model
Comparison
New automated method for quantification of… vs Reference values from experimental data
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Hypothesis-generating for automated mitral regurgitation quantification; clinical validation required before any use.
Structured PICO
P
Population
Computational fluid dynamics simulations and experimental data from an in vitro flow model
I
Intervention
New automated method for quantification of mitral regurgitant volume and dynamic regurgitant orifice area based on a normalized centerline velocity distribution using Color M-mode and Continuous Wave Doppler Imaging
C
Comparator
Reference values from experimental data
O
Outcome
Estimation of orifice diameter and regurgitant volumesurrogate
Main Result
Effect estimate: r = 0.96 (diameter), r = 0.93 (volume)
A novel automated echocardiographic method using normalized centerline velocity distribution accurately estimates mitral regurgitant orifice diameter and volume in an in vitro model, overcoming limitations of the PISA technique.
Cite This Study
Deserranno et al. (2003) studied Mitral Regurgitation. New automated method using Color M-mode and Continuous Wave Doppler vs. Reference values was evaluated on Orifice diameter and regurgitant volume (r = 0.96 (diameter), r = 0.93 (volume)). A new automated model for estimating mitral regurgitant orifice diameter and volume showed close agreement with reference values in an in vitro flow model (r=0.96 and r=0.93, respectively).