Key result
A new control volume method using MRI accurately measured flow rate through regurgitant orifices in vitro and in vivo, correlating well with actual rates (r=0.992).
Why the study?
Does a new control volume method using MRI accurately measure valvular regurgitation compared to actual flow rates and thermodilution?
Population
In vitro models with steady and pulsatile flows, and an in vivo model
Comparison
Control volume method using magnetic resonance… vs Actual flow rate and thermodilution measurements
Design
Preclinical
Authors
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Promising for regurgitation quantification in models; leaves open human validation before clinical use.
Does a new control volume method using MRI accurately measure valvular regurgitation compared to actual flow rates and thermodilution?
Effect estimate: r=0.992
A novel control volume method using MRI accurately quantifies valvular regurgitation in vitro and in a porcine model, overcoming limitations of the PISA method.
Walker et al. (1995) studied Valvular regurgitation. Control volume method using MRI vs. Thermodilution / actual flow rate was evaluated on Flow rate through the orifice (r=0.992). A new control volume method using MRI accurately measured flow rate through regurgitant orifices in vitro and in vivo, correlating well with actual rates (r=0.992).
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