Why the study?
Does dominant frequency spatiotemporal stability differ among patients with persistent AF with LVSD, persistent AF without LVSD, and paroxysmal AF without LVSD?
Population
40 patients, including 15 with persistent atrial fibrillation and left ventricular systolic dysfunction, 15…
Comparison
Dominant frequency mapping at 536 sites at… vs Comparison between persistent AF with LVSD…
Design
Cross-sectional
Follow-up
26 +/- 12 min
Key result
Dominant frequency spatiotemporal stability was significantly higher in persistent AF with and without LVSD (77% and 70% of sites) compared to paroxysmal AF (48%, P<0.001).
Authors
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Supports stable sources in persistent AF; hypothesis-generating for dominant frequency mapping to guide ablation.
Observational (n=40)
Does dominant frequency spatiotemporal stability differ among patients with persistent AF with LVSD, persistent AF without LVSD, and paroxysmal AF without LVSD?
Absolute Event Rate: 77% vs 70%
p-value: p=<0.001
Dominant frequency mapping demonstrates that persistent AF, with or without LVSD, is maintained by stable arrhythmia sources, unlike paroxysmal AF.
Arenal et al. (2008) conducted an observational in Atrial fibrillation (n=40). Dominant frequency mapping vs. Persistent AF without LVSD and Paroxysmal AF without LVSD was evaluated on Dominant frequency spatiotemporal stability (DF1-DF2 difference of ≤0.5 Hz) (p=<0.001). Dominant frequency spatiotemporal stability was significantly higher in persistent AF with and without LVSD (77% and 70% of sites) compared to paroxysmal AF (48%, P<0.001).