Electrocardiographic Predictors of Heart Failure With Reduced Versus Preserved Ejection Fraction: The Multi‐Ethnic Study of Atherosclerosis
Why the study?
Do baseline ECG markers predict and distinguish the future risk of HFrEF versus HFpEF in individuals free of cardiovascular disease?
Population
6,664 participants from MESA who were free of cardiovascular disease at baseline, 53% female, mean age 62±10…
Design
Cohort
Follow-up
median 12.1 years
Authors
Discussion
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Member takes
Implication
ECG markers may stratify future HFrEF versus HFpEF risk; leaves open added predictive value in primary prevention.
Structured PICO
Do baseline ECG markers predict and distinguish the future risk of HFrEF versus HFpEF in individuals free of cardiovascular disease?
P
Population
6,664 participants from MESA (Multi-Ethnic Study of Atherosclerosis) who were free of cardiovascular disease at baseline, 53% female, mean age 62±10 years.
I
Intervention
Baseline 12-lead ECG markers (including QRS duration, intrinsicoid deflection, axis deviation, QT interval, QRS-T axis, LVH, ST/T-wave abnormalities, bundle-branch block, resting heart rate, P-wave axis)
O
Outcome
Incident heart failure with reduced ejection fraction (HFrEF) versus heart failure with preserved ejection fraction (HFpEF) during a median follow-up of 12.1 yearshard clinical
Baseline ECG markers of ventricular repolarization and delayed ventricular activation can distinguish between the future risk of developing HFrEF versus HFpEF in individuals without baseline cardiovascular disease.
Cite This Study
O’Neal et al. (2017) studied this question.