Key result
Female sex was an independent predictor of congestive heart failure (OR 1.72; 95% CI 1.11-2.66; p=0.02) in patients undergoing diagnostic cardiac catheterization.
Why the study?
Does female sex influence the prevalence of congestive heart failure and left ventricular pressure/volume relation in patients undergoing diagnostic cardiac catheterization?
Observational (n=1,667)
Does female sex influence the prevalence of congestive heart failure and left ventricular pressure/volume relation in patients undergoing diagnostic cardiac catheterization?
Effect estimate: OR 1.72 (95% CI 1.11 to 2.66)
Absolute Event Rate: 13% vs 10%
p-value: p=0.02
Women undergoing diagnostic cardiac catheterization have a higher prevalence of congestive heart failure symptoms despite better preserved left ventricular systolic function, suggesting diastolic dysfunction as a key mechanism.
No takes yet. Share an insight, caveat, or question.
May warrant sex-specific HF monitoring during catheterization; hypothesis-generating for diastolic mechanisms and needs prospective confirmation.
Mendes et al. (1997) conducted an observational in coronary artery disease (n=1,667). Female sex vs. Male sex was evaluated on symptoms of congestive heart failure (OR 1.72, 95% CI 1.11 to 2.66, p=0.02). Female sex was an independent predictor of congestive heart failure (OR 1.72; 95% CI 1.11-2.66; p=0.02) in patients undergoing diagnostic cardiac catheterization.
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