Key result
Microalbuminuria is linked to ~39% higher plasma aldosterone levels in treatment-naïve hypertensive patients.
Why the study?
Is plasma aldosterone associated with microalbuminuria in nondiabetic, treatment-naïve patients with hypertension?
Cross-Sectional (n=242)
Is plasma aldosterone associated with microalbuminuria in nondiabetic, treatment-naïve patients with hypertension?
Absolute Event Rate: 178% vs 128%
p-value: p=0.001
In nondiabetic, treatment-naïve hypertensive patients, low-grade albuminuria is independently associated with elevated plasma aldosterone, suggesting a role for aldosterone in early hypertensive nephropathy.
No takes yet. Share an insight, caveat, or question.
May implicate aldosterone in early nephropathy; hypothesis-generating and should not yet change practice.
Catena et al. (2017) conducted a cross-sectional in Uncomplicated primary hypertension (n=242). Microalbuminuria vs. No microalbuminuria was evaluated on Plasma aldosterone levels (p=0.001). Plasma aldosterone levels were significantly higher in treatment-naïve hypertensive patients with microalbuminuria compared to those without (178 vs. 128 pg/ml; P=0.001).
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