Key result
Plasma PICP levels 2 weeks after admission independently predicted the progression of left ventricular remodeling after myocardial infarction (p < 0.001).
Why the study?
Do circulating levels of PICP predict the progression of left ventricular remodeling in patients with first myocardial infarction?
Population
20 patients with first myocardial infarction undergoing reperfusion therapy
Design
Cohort
Follow-up
4 weeks
Authors
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May aid post-MI risk stratification; leaves open whether targeting PICP alters remodeling.
Observational (n=20)
Do circulating levels of PICP predict the progression of left ventricular remodeling in patients with first myocardial infarction?
p-value: p=<0.001
An increase in plasma PICP levels 2 weeks after admission serves as a useful biochemical predictor for the progression of left ventricular remodeling following a first myocardial infarction.
Takino et al. (1999) conducted an observational in Myocardial Infarction (n=20). Plasma PICP levels was evaluated on Changes (Delta) in left ventricular end-diastolic volume index (EDVI) (p=<0.001). Plasma PICP levels 2 weeks after admission independently predicted the progression of left ventricular remodeling after myocardial infarction (p < 0.001).
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