Key result
Complete VT noninducibility after ablation in NIDCM linked to ~63% lower mortality vs inducible VT.
Why the study?
Does complete VT noninducibility after catheter ablation reduce all-cause mortality in patients with nonischemic dilated cardiomyopathy?
Population
102 patients with nonischemic dilated cardiomyopathy undergoing catheter ablation for ventricular…
Comparison
Complete VT noninducibility achieved via… vs Partial success or failure after catheter ablation
Design
Cohort
Follow-up
2 years
Authors
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Supports noninducibility as ablation endpoint in NIDCM; leaves open whether it improves survival in prospective trials.
Cohort (n=102)
Does complete VT noninducibility after catheter ablation reduce all-cause mortality in patients with nonischemic dilated cardiomyopathy?
Effect estimate: adjusted HR 2.73 (95% CI 1.003-7.43)
Absolute Event Rate: 15% vs 34%
p-value: p=0.049
Achieving complete VT noninducibility during catheter ablation in patients with nonischemic dilated cardiomyopathy is associated with reduced long-term all-cause mortality and VT recurrence.
Dinov et al. (2015) conducted a cohort in Nonischemic dilated cardiomyopathy with ventricular tachycardia (n=102). Catheter ablation achieving complete VT noninducibility vs. Catheter ablation with inducible VT (partial success or failure) was evaluated on All-cause mortality (adjusted HR 2.73, 95% CI 1.003-7.43, p=0.049). Complete VT noninducibility after catheter ablation in patients with NIDCM was associated with lower all-cause mortality compared to inducible VT (15% vs 34%; adjusted HR 2.73; P=0.049).