Key result
Right ventricular septal pacing resulted in better left ventricular longitudinal function (Sm 4.9 vs 4.2 cm/sec) compared to apical pacing, with no significant difference in acute dyssynchrony.
Why the study?
Does right ventricular septal pacing improve left ventricular dyssynchrony compared to apical pacing in patients undergoing pacemaker implantation?
Observational (n=94)
Single-blind
Yes
Does right ventricular septal pacing improve left ventricular dyssynchrony compared to apical pacing in patients undergoing pacemaker implantation?
Absolute Event Rate: 4.9% vs 4.2%
p-value: p=<0.05
In patients undergoing pacemaker implantation, right ventricular septal pacing resulted in a smaller increase in QRS duration compared to apical pacing, but acute echocardiographic indices of left ventricular dyssynchrony did not differ between the sites.
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RV septal pacing was associated with modestly better LV function; leaves open whether it reduces dyssynchrony or improves outcomes.
Cho et al. (2011) conducted an observational in Sick sinus syndrome or high degree atrio-ventricular block (n=94). Right ventricular septal pacing vs. Right ventricular apical pacing was evaluated on Averaged peak systolic tissue velocity (Sm) (p=<0.05). Right ventricular septal pacing resulted in better left ventricular longitudinal function (Sm 4.9 vs 4.2 cm/sec) compared to apical pacing, with no significant difference in acute dyssynchrony.
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