Key result
Single-chamber ventricular pacemakers provided similar stroke volume and cardiac output compared to dual-chamber pacemakers, but a higher left cardiac work index.
Why the study?
Does single-chamber ventricular pacing provide similar hemodynamic parameters compared to dual-chamber pacing in outpatients?
Cross-Sectional (n=48)
Does single-chamber ventricular pacing provide similar hemodynamic parameters compared to dual-chamber pacing in outpatients?
Non-invasive hemodynamic measurement using thoracic electrical bioimpedance is feasible and shows single-chamber ventricular pacemakers provide similar stroke volume and cardiac output to dual-chamber pacemakers.
Answers are grounded in this paper and cite their sources.
Single-chamber pacing may yield similar hemodynamics to dual-chamber in outpatients; leaves open clinical relevance of higher left cardiac work index.
We carried out a cross sectional study to analyze hemodynamic parameters of single-chamber ventricular pacemaker compared with dual-chamber pacemaker by using thoracic electrical bioimpedance monitoring method (Physio Flow™) - a novel simple non-invasive measurement. A total of 48 consecutive outpatients comprised of 27 single chamber pacemaker and 21 dual chamber were analyzed. We measured cardiac parameters: heart rate, stroke volume index, cardiac output index, estimated ejection fraction, end diastolic volume, early diastolic function ratio, thoracic fluid index, and systemic parameters: left cardiac work index and systemic vascular resistance index. Baseline characteristic and pacemaker indication were similar in both groups. Cardiac parameters assessment revealed no significant difference between single-chamber pacemaker and dual-chamber pacemaker in heart rate, stroke volume index, cardiac index, estimated ejection fraction, end-diastolic volume, thoracic fluid index. There was significantly higher early diastolic function ratio in single-chamber pacemaker compared to dual-chamber pacemaker: 92% (10.2-187.7%) vs. 100.6% (48.7-403.2%); p=0.006. Systemic parameters assessment revealed significantly higher left cardiac work index in single-chamber group than dual-chamber group 4.9 kg.m/m² (2.8-7.6 kg.m/m²) vs. 4.3 kg.m/m² (2.9-7.2 kg.m/m²); p=0.004. There was no significant difference on systemic vascular resistance in single-chamber compared to dual-chamber pacemaker. Single-chamber ventricular pacemaker provides similar stroke volume, cardiac output and left cardiac work, compared to dual-chamber pacemaker. A non-invasive hemodynamic measurement using thoracic electrical bioimpedance is feasible for permanent pacemaker outpatients. (Med J Indones 2008; 17: 25-32)
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Pardede et al. (2008) conducted a cross-sectional in Permanent pacemaker outpatients (n=48). Single-chamber ventricular pacemaker vs. Dual-chamber pacemaker was evaluated on Hemodynamic parameters measured by thoracic electrical bioimpedance. Single-chamber ventricular pacemakers provided similar stroke volume and cardiac output compared to dual-chamber pacemakers, but a higher left cardiac work index.
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