Why the study?
The study was conducted to undertake a preliminary assessment of left ventricular hemodynamic status during right ventricular double-chamber pacing using vector flow mapping and to evaluate vector flow mapping technology in measuring post-implantation cardiac function.
Does right ventricular double-chamber pacing alter left ventricular hemodynamics compared to healthy controls?
Observational (n=116)
Does right ventricular double-chamber pacing alter left ventricular hemodynamics compared to healthy controls?
Right ventricular double-chamber pacing is associated with abnormal left ventricular hemodynamics, including increased energy loss and decreased wall shear stress, which may reduce systolic efficiency.
Answers are grounded in this paper and cite their sources.
RV double-chamber pacing may disrupt LV hemodynamics; leaves open clinical relevance and need for prospective validation.
PURPOSE: We set out to undertake a preliminary assessment of the left ventricular hemodynamic status with right ventricular double-chamber pacing by energy loss (EL), wall shear stress (WSS), and circulation intensity (CIR) of vector flow mapping (VFM). We also planned to evaluate the value of VFM technology by measuring cardiac function after pacemaker implantation. METHOD: Data from 58 patients living with right ventricular double-chamber (right ventricular septal) pacemakers as well as 58 healthy volunteers matched in age and gender were collected. The EL, numbers of vortex cycles (n), area (A), CIR, and WSS of the left ventricle with different phases of the same cardiac cycle were obtained. RESULTS: The EL of the left ventricle was significantly higher in the pacemaker group than the control group at partial section of atrial contraction (AC), isovolumetric contraction (IVC), and rapid ejection (RE) (P < 0.05). The WSS of the left ventricle was significantly lower in the pacemaker group than the control group at part of the section in the rapid filling (RF), the AC, IVC, and RE phase (P < 0.05). DISCUSSION: EL in the left ventricular was significantly increased, while related WSS was significantly decreased in patients with right ventricular double-chamber pacing. Our exploration of the state of the flow field in the left ventricular cavity revealed that the implantation of the right ventricular double-chamber pacemaker led to an abnormal left ventricular hemodynamic state, reducing the left ventricular systolic efficiency.
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Meng et al. (2019) conducted an observational in Right ventricular double-chamber pacing (n=116). Right ventricular double-chamber pacing vs. Healthy volunteers was evaluated on Left ventricular hemodynamic status assessed by energy loss (EL) and wall shear stress (WSS) (p=<0.05).
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