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March 6, 2019Journal of Medical EconomicsOpen Access

Hospital costs associated with intraoperative hypotension among non-cardiac surgical patients in the US: a simulation model

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Key result

Improved intraoperative hypotension control in non-cardiac surgery is linked to savings of ~$272 per patient.

  • Cost reduction of $272 per patient (unadjusted AKI model)
  • 95% CI $223-$321

Why the study?

Intraoperative hypotension in non-cardiac surgery is linked to myocardial injury, acute kidney injury, and mortality, but its association with US hospital expenditures needed quantification.

Does improved intraoperative hypotension control reduce hospital costs associated with AKI and MINS in non-cardiac surgical patients?

Population

Simulated non-cardiac surgical patients in the US (10,000 trial per simulation)

Comparison

Intraoperative hypotension vs hypotension control

Design

Monte Carlo simulation model

Authors

EKEric L. KeuffelJRJohn A. RizzoMSMitali Stevens

Discussion

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Overview

Supports potential cost savings from hypotension control in non-cardiac surgery; leaves open causal confirmation via randomized trials.

Structured PICO

Does improved intraoperative hypotension control reduce hospital costs associated with AKI and MINS in non-cardiac surgical patients?

P
Population
Simulated cohort of non-cardiac surgical patients in the US (10,000 trials per simulation)
I
Intervention
Improved intraoperative hypotension control
C
Comparator
Intraoperative hypotension
O
Outcome
Hospital expenditures/costs associated with intraoperative hypotension (via AKI and MINS)

Main Result

Effect estimate: Cost reduction of $272 per patient (unadjusted AKI model) (95% CI $223-$321)

Improved intraoperative hypotension control in non-cardiac surgery may yield significant hospital cost savings by reducing the incidence of AKI and myocardial injury.

Cite This Study

Keuffel et al. (2019) studied Intraoperative hypotension in non-cardiac surgery. Intraoperative hypotension control vs. Intraoperative hypotension was evaluated on Hospital expenditures associated with intraoperative hypotension (Cost reduction of $272 per patient (unadjusted AKI model), 95% CI $223-$321). Improved intraoperative hypotension control in non-cardiac surgery is associated with mean hospital cost reductions ranging from $1.2 to $4.6 million per year per 10,000 patients.

synapsesocial.com/papers/6a0ed138218372ada647c024https://doi.org/10.1080/13696998.2019.1591147
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