Key result
Intraoperative reductions in blood pressure from baseline of 41 to 50 mm Hg resulted in a 3-fold risk of developing acute myocardial infarction after noncardiac surgery.
Why the study?
Does intraoperative hypotension increase the risk of acute perioperative myocardial infarction in patients undergoing noncardiac surgery?
Case-Control
Yes
Does intraoperative hypotension increase the risk of acute perioperative myocardial infarction in patients undergoing noncardiac surgery?
Effect estimate: 3-fold risk
Intraoperative hypotension, specifically reductions of 41-50 mm Hg from baseline, is strongly associated with an increased risk of perioperative myocardial infarction during noncardiac surgery.
In this issue of Anesthesia & Analgesia, Hallqvist et al perform a nested case-control study assessing patients who suffered acute, perioperative myocardial infarction after undergoing noncardiac surgery. Patients were identified from the registries of 3 university hospitals in Sweden from 2007 to 2014. They were matched to controls based on age, sex, ASA class, cardiovascular disease, surgical year, hospital, surgical code, acuity of surgery, and surgical duration. The authors explored the relationship of intraoperative hypotension to the consequent risk of acute MI. Reductions in blood pressure were defined relative to baseline values obtained from ≥5 prior readings within 2 months of presenting for surgery. As this infographic summarizes, reductions in blood pressure from baseline of 41 to 50 mm Hg resulted in a 3-fold risk of developing acute myocardial infarction, and further reductions significantly amplified this risk. The reader is strongly encouraged to pursue and in-depth understanding of these findings by reviewing the article and its attendant editorial.
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Naveen Nathan (2021) conducted a case-control in Perioperative myocardial infarction after noncardiac surgery. Intraoperative hypotension (reductions in blood pressure from baseline of 41 to 50 mm Hg) vs. Matched controls was evaluated on Acute myocardial infarction (3-fold risk). Intraoperative reductions in blood pressure from baseline of 41 to 50 mm Hg resulted in a 3-fold risk of developing acute myocardial infarction after noncardiac surgery.
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