Why the study?
Do children and adolescents with hypertension manifest neurocognitive differences compared with normotensive controls?
Do children and adolescents with hypertension manifest neurocognitive differences compared with normotensive controls?
Emerging evidence suggests that pediatric hypertension is associated with neurocognitive deficits, learning difficulties, and altered cerebrovascular reactivity, similar to findings in adults.
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Pediatric hypertension may warrant neurocognitive screening; leaves open whether BP lowering reverses deficits.
Hypertensive adults demonstrate performance deficits on neuropsychological testing compared with scores of normotensive controls. This article reviews emerging preliminary evidence that children with hypertension also manifest neurocognitive differences when compared with normotensive controls. Database and single-center studies suggest that children with hypertension manifest deficits on measures of neurocognition and have an increased prevalence of learning difficulties and that children with hypertension associated with obesity may be at increased risk for depression and anxiety. Studies suggesting blunted cerebrovascular reactivity in children with hypertension are also reviewed.
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Lande et al. (2012) studied this question.
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