Key result
Single-session debridement and sterilization achieves 92% success for isolated CIED pocket infections without device replacement.
Why the study?
Increasing rates of CIED infection carry high management costs, prompting the evaluation of a single-session protocol to reuse the infected pocket side, device, and leads.
Does a single-session protocol of pocket debridement and device sterilization prevent recurrence of infection in patients with isolated CIED pocket infection?
Observational (n=12)
Does a single-session protocol of pocket debridement and device sterilization prevent recurrence of infection in patients with isolated CIED pocket infection?
A single-session protocol involving pocket debridement and device sterilization with gas plasma successfully treated 92% of isolated CIED pocket infections without requiring device replacement or a new pocket site.
May support CIED salvage in isolated pocket infections; leaves open confirmation in prospective trials.
BACKGROUND: The dramatic increase in the use of cardiovascular implantable electronic devices (CIED) was associated with an increased rate of CIED infection, which has a high management cost. AIM OF THE STUDY: To test the safety and efficacy of a single-session protocol, aiming to reuse the infected pocket side and the same device and leads in patients with CIED pocket infection. PATIENTS AND METHODS: We included patients with isolated pocket infection between January 2015 and November 2019. The Patient was prepared by taking a swab for culture and sensitivity before the procedure. The pocket was debrided and the capsule was removed, the pocket was rinsed with povidone-iodine and hydrogen peroxide mixture, then packed with gauze sponge soaked with povidone-iodine. The device was debrided using ultrasonic irrigation and sterilized using gas plasma. The device was reimplanted and the wound was closed in layers. RESULTS: During the period of the study, we had 12 patients with isolated pocket infection. Nine presented with erosion, two with impending erosion, and one with a chronic sinus. Patient's age was 61.5 ± 7.64 years. The infection was diagnosed 14.2 ± 8.22 weeks post device implantation. They were admitted for 7.6 ± 1.54 days postprocedure. The follow-up duration was 26.5 ± 15 (1.7-52) months. Only one patient (8%) had a recurrence of the infection after 50 days of the procedure. CONCLUSION: Our protocol was successful in treating 92% of device-related pocket infection without the need to replace the device or the pocket side.
No takes yet. Share an insight, caveat, or question.
Roshdy et al. (2020) conducted an observational in CIED pocket infection (n=12). Single-session protocol (pocket debridement, device sterilization, and reimplantation) was evaluated on Successful treatment of infection without device or pocket side replacement. A single-session protocol involving pocket debridement and device sterilization successfully treated 92% of isolated CIED pocket infections without needing device or pocket side replacement.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: