Key result
Device-detected paroxysmal AF is linked to ~4-fold higher ischemic stroke risk within 30 days.
Why the study?
Studies evaluating the temporal association between paroxysmal atrial fibrillation and ischemic stroke were inconclusive.
Is there a temporal association between paroxysmal atrial fibrillation episodes and ischemic stroke within 30 days in patients with continuous cardiac implantable electronic devices?
Population
4041 patients across 7 studies (138 with device-detected PAF episodes and stroke)
Comparison
Temporal association between AF episodes and stroke within 30 days vs 90 days
Design
Systematic review and meta-analysis
Authors
Loading...
Supports closer post-AF stroke monitoring in CIED patients; extends temporal association data but leaves optimal management open.
Meta-Analysis (n=4,041)
Is there a temporal association between paroxysmal atrial fibrillation episodes and ischemic stroke within 30 days in patients with continuous cardiac implantable electronic devices?
Effect estimate: OR 4.11 (95% CI 1.03-16.40)
This meta-analysis demonstrates a significant temporal relationship between paroxysmal atrial fibrillation and ischemic stroke within a 30-day window, highlighting the potential for individualized risk prediction and targeted anticoagulation.
D'Lima et al. (2024) conducted a meta-analysis in Paroxysmal atrial fibrillation and ischemic stroke (n=4,041). Device-detected paroxysmal atrial fibrillation episodes was evaluated on Temporal association between AF episodes and stroke within 30 days of the arrhythmic episode (OR 4.11, 95% CI 1.03-16.40). Device-detected paroxysmal atrial fibrillation episodes were significantly associated with ischemic stroke within a 30-day window (OR 4.11; 95% CI 1.03-16.40).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: