Key result
Early discharge within 48 hours post-PCI links to ~5% 30-day MACE in low-risk patients.
Why the study?
Early discharge after primary PCI could offer substantial financial benefits in low-middle income countries, but local evidence regarding its feasibility and safety was lacking in Karachi, Pakistan.
Is early discharge (≤ 48 hours) after primary PCI safe in selected low-risk patients?
Population
600 consecutive low-risk patients discharged within 48 hours of primary PCI in Karachi, Pakistan
Comparison
Very early discharge (≤ 24 hours) vs early discharge (24 to 48 hours)
Design
Observational study
Follow-up
30 days
Authors
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May support early discharge after primary PCI in low-risk patients; leaves open need for randomized confirmation.
Observational (n=600)
Is early discharge (≤ 48 hours) after primary PCI safe in selected low-risk patients?
Very early discharge (≤ 24 hours) after primary PCI is safe and feasible in selected low-risk patients, demonstrating low 30-day MACE rates.
Shah et al. (2021) conducted an observational in Primary percutaneous coronary intervention (PCI) (n=600). Early discharge (≤ 48 hours) was evaluated on Major adverse cardiac events (MACE) at 30 days. Early discharge within 48 hours after primary PCI in low-risk patients was associated with a cumulative 30-day MACE rate of 4.9% and all-cause mortality of 2.3%.
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