Key result
Improved EF and reverse cardiac remodeling in HF linked to ~49% lower mortality.
Why the study?
Does guideline-directed medical therapy promote reverse remodeling and improve prognosis in patients with heart failure?
Does guideline-directed medical therapy promote reverse remodeling and improve prognosis in patients with heart failure?
Improved ejection fraction is a critical marker of therapeutic success and better prognosis in heart failure, underscoring the importance of optimizing guideline-directed medical therapy.
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Antônio Carlos Pereira Barretto (2022) conducted a review in Heart Failure. Optimized medical therapy (neurohormonal blockade) was evaluated. Improved ejection fraction and reverse cardiac remodeling in heart failure patients are associated with a 49% reduction in mortality compared to patients without improvement.
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