Key result
Personalized multidisciplinary HF management in CKD ensures safe drug dosing based on renal clearance.
Why the study?
Managing patients with concurrent heart failure and chronic kidney disease is challenging, particularly regarding the safe administration of new heart failure drugs according to renal function thresholds.
How should heart failure be assessed and managed in patients with concurrent chronic kidney disease?
How should heart failure be assessed and managed in patients with concurrent chronic kidney disease?
This review provides a summary of assessment and management strategies for patients with concurrent heart failure and chronic kidney disease, focusing on the safe use of new heart failure therapies.
Supports safe use of new HF therapies in CKD; leaves open prospective validation of multidisciplinary strategies.
CKD in HF patients is very common condition, their dysfunction is closely linked and influence each other, so their management required multidisciplinary and personalized approaches. The diagnosis of HF and CDK relies on signs and symptoms. Several tools, such as blood-based biomarkers and echography help us to clarify and discriminate the main characteristics of these patients. Evidence in improving survival due to new drug-employment in HF, has increasingly challenged physicians to manage patients with multiple diseases, especially in patients with CKD. The difficulty is in the safe administration of these drugs in patients with HF and CKD. Knowing up to which values of creatinine or renal clearance any drug can be administered is fundamental. We wanted to summarize, on this sizable and complex topic, the experiences of various prior study to get clearer ideas and a more precise reference about the assessment and management of HF and CKD.
No takes yet. Share an insight, caveat, or question.
Guaricci et al. (2023) conducted a review in Heart Failure and Chronic Kidney Disease. Assessment and management strategies was evaluated. Multidisciplinary assessment and personalized management of heart failure in patients with chronic kidney disease are essential for safe drug administration based on renal clearance.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: