Clinical outcomes of acute myocarditis in childhood
Key result
Paediatric patients with acute lymphocytic myocarditis treated primarily with immunosuppression had a 79% freedom from death or cardiac transplantation at two years, with good ventricular recovery.
Why the study?
What are the clinical outcomes of pediatric patients with acute lymphocytic myocarditis?
Population
36 pediatric patients with histologically confirmed lymphocytic myocarditis presenting with acute heart…
Design
Cohort
Follow-up
median 19 months (range 1.2–131.6 months) for survivors
Authors
Discussion
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Implication
Supports primary immunosuppression in pediatric lymphocytic myocarditis; hypothesis-generating, requiring randomized confirmation before practice change.
Study Design
Type
Observational (n=36)
Multicenter
No
Structured PICO
What are the clinical outcomes of pediatric patients with acute lymphocytic myocarditis?
P
Population
36 pediatric patients with histologically confirmed lymphocytic myocarditis presenting with acute heart failure
I
Intervention
Intravenous corticosteroids (immunosuppression) in 34 patients
O
Outcome
Survival, cardiac transplantation, recovery of ventricular function, and persistence of dysrhythmiashard clinical
Pediatric patients with acute lymphocytic myocarditis have good outcomes, including high rates of survival and recovery of ventricular function.
Cite This Study
Lee et al. (1999) conducted an observational in Acute lymphocytic myocarditis (n=36). Immunosuppression (intravenous corticosteroids) was evaluated on Survival, cardiac transplantation, recovery of ventricular function, and persistence of dysrhythmias. Paediatric patients with acute lymphocytic myocarditis treated primarily with immunosuppression had a 79% freedom from death or cardiac transplantation at two years, with good ventricular recovery.