June 1, 1987Circulation

Quantitative analysis of narrowings of intramyocardial small arteries in normal hearts, hypertensive hearts, and hearts with hypertrophic cardiomyopathy.

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Population

39 autopsied hearts

Design

Cross-sectional

Authors

MTMasaru TanakaUniversity of Szeged HFHisayoshi FujiwaraHeart Failure / Cardiomyopathy TOTomoya OnoderaEarthquake Engineering Research Institute

Discussion

Member takes

Implication

May contribute to ischemia in HCM; leaves open whether IMSA narrowing precedes or follows hypertrophy and fibrosis.

Structured PICO

Population

39 autopsied hearts (10 from patients with typical hypertrophic cardiomyopathy [HCM], 4 from patients with HCM showing features mimicking dilated cardiomyopathy [DCM-like HCM], 10 from patients with hypertension, and 15 from normal adults)

Comparator

Normal adult hearts

Outcome

External caliber and ratio of the luminal area to the total vascular area (percent luminal area, % lumen) of intramyocardial small arteries (IMSAs)surrogate

Intramyocardial small artery narrowing is significantly associated with myocardial hypertrophy and fibrosis in patients with hypertrophic cardiomyopathy and hypertension.

Cite This Study

Tanaka et al. (1987) studied this question.

synapsesocial.com/papers/6a0f1f68a7a2fed64abdbb6e https://doi.org/10.1161/01.cir.75.6.1130

Topics

Hypertension management Hypertrophic cardiomyopathy

View Full Paper

Ask AI

Bookmark

Quantitative analysis of narrowings of intramyocardial small arteries in normal hearts, hypertensive hearts, and hearts with hypertrophic cardiomyopathy.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Quantitative analysis of narrowings of intramyocardial small arteries in normal hearts, hypertensive hearts, and hearts with hypertrophic cardiomyopathy.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider