Key result
Primary angioplasty for AMI achieves LVEF >40% in 77% of patients at three months.
Why the study?
Left ventricular function is the primary predictor of long-term prognosis after acute myocardial infarction, prompting investigation into ejection fraction recovery during the first 3 months post-primary angioplasty.
Does primary angioplasty improve left ventricular ejection fraction in patients with acute ST-segment elevation myocardial infarction?
Cross-Sectional (n=100)
No
Does primary angioplasty improve left ventricular ejection fraction in patients with acute ST-segment elevation myocardial infarction?
Primary angioplasty for acute ST-segment elevation myocardial infarction is associated with significant recovery of left ventricular ejection fraction at 3 months.
Supports LVEF recovery after primary angioplasty in STEMI; hypothesis-generating and requires RCTs before practice change.
Background: This study is to investigate the recovery in left ventricular ejection fraction in the first 3 months after acute myocardial infarction treated with primary angioplasty. Left ventricular function (LVF) is the main predictor of long term prognosis in cases of survival after acute myocardial infarction. Study aims to investigate successful improvement in left ventricular ejection fraction after primary angioplasty. Methodology: A cross sectional study was conducted at Chaudhary Pervaiz Ellahi Institute of Cardiology, Multan from 1stSeptember 2019 to 30thSeptember 2020. Left ventricular ejection fraction was evaluated in 100 patients treated with primary angioplasty. Primary angioplasty is a very 1st treatment to re-open the locked artery after acute myocardial infarction. Ejection fraction was measured with Echocardiography Simpson’s biplane method at 3rd day and 3 months after angioplasty. Collected data was analyzed by using SPSS version 23. Chi square test was applied to see association among variables. Results: One hundred patients were included this study. The mean age and BMI of the patients was 59.45±6.01 years and 24.76±8.02 kg/m2, respectively. Male 70 (70%) and female 30 (30%) ratio was 7:3. LVEF at 3rd month was observed in ≤40% in 223 (23.0%) patients and >40% in 77 (77%) patients. Male patients were greater in number that’s why LVEF is also observed in greater in male gender (p<0.001). Increase in age also have no impact on procedure success (p>0.050). Conclusion: Results of this study reveal that primary angioplasty is successful treatment plan in patients with acute myocardial infarction. A significant recovery of left ventricular function during 3 months after primary angioplasty in acute Myocardial infarction (MI) patients was observed.
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Ramzan et al. (2023) conducted a cross-sectional in Acute myocardial infarction (n=100). Primary angioplasty was evaluated on Left ventricular ejection fraction >40% at 3 months. Primary angioplasty for acute myocardial infarction resulted in a left ventricular ejection fraction >40% in 77% of patients at 3 months.
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