Key result
Plasma adiponectin concentrations were significantly lower in essential hypertension versus controls (P<0.001) and decreased progressively with higher grades of hypertensive retinopathy (P<0.001).
Why the study?
Are plasma adiponectin levels associated with the presence and severity of hypertensive retinopathy in patients with essential hypertension?
Population
110 patients newly diagnosed with essential hypertension and 57 healthy normotensive control subjects.
Design
Cross-sectional
Authors
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Lower adiponectin was associated with retinopathy severity in hypertension; hypothesis-generating and should not yet change practice.
Observational (n=167)
Are plasma adiponectin levels associated with the presence and severity of hypertensive retinopathy in patients with essential hypertension?
p-value: p=<0.001
Lower plasma adiponectin levels are associated with the presence and severity of hypertensive retinopathy in patients with essential hypertension.
Yılmaz et al. (2005) conducted an observational in Essential hypertension and hypertensive retinopathy (n=167). Plasma adiponectin levels vs. Normotensive controls was evaluated on Plasma adiponectin concentrations across hypertensive retinopathy grades and compared to normotensive controls (p=<0.001). Plasma adiponectin concentrations were significantly lower in essential hypertension versus controls (P<0.001) and decreased progressively with higher grades of hypertensive retinopathy (P<0.001).
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