Key result
Nurse-coordinated management linked to ~100% greater achievement of target ACEi/ARB and beta-blocker doses.
Why the study?
Does nurse-coordinated management improve guideline-recommended heart failure therapy, patient-reported outcomes, and left ventricular remodelling in patients hospitalized for decompensated HF with LVEF ≤40%?
Population
706 patients hospitalized for decompensated heart failure with LVEF ≤40% before discharge, surviving >18…
Comparison
Nurse-coordinated management (HeartNetCare-HF) vs Usual Care
Design
Cohort
Follow-up
18 months
Authors
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May support nurse-coordinated GDMT programs in HFrEF; hypothesis-generating pending randomized confirmation.
Cohort (n=706)
Does nurse-coordinated management improve guideline-recommended heart failure therapy, patient-reported outcomes, and left ventricular remodelling in patients hospitalized for decompensated HF with LVEF ≤40%?
Absolute Event Rate: 50% vs 25%
p-value: p=<0.001
Nurse-coordinated disease management significantly improves adherence to guideline-directed medical therapy target doses, left ventricular ejection fraction, and patient-reported quality of life in patients with heart failure with reduced ejection fraction.
Güder et al. (2015) conducted a cohort in Heart failure (n=706). Nurse-coordinated management (HeartNetCare-HF) vs. Usual Care was evaluated on Achievement of guideline-recommended target doses for ACEi/ARB (p=<0.001). Nurse-coordinated management significantly increased the achievement of guideline-recommended target doses for ACEi/ARB (50% vs 25%, P<0.001) and beta-blockers (39% vs 15%, P<0.001) at 18 months.
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