November 18, 1997Circulation
Mechanisms Causing Sustained Ventricular Tachycardia With Multiple QRS Morphologies
Key result
In 11 canine hearts with 4-day-old infarcts, tachycardias with multiple QRS morphologies most commonly arose from reentrant circuits in the same region of the infarct with different exit routes.
Population
11 canine hearts with 4-day-old myocardial infarcts
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Suggests single-site ablation may address multi-morphology VT; leaves open human translation.
Structured PICO
P
Population
11 canine hearts with 4-day-old myocardial infarcts
I
Intervention
Induction of reentrant ventricular tachycardia and mapping of reentrant circuits
O
Outcome
Mechanisms causing tachycardias with multiple QRS morphologies based on activation maps of reentrant circuits in the epicardial border zone
In a canine model of myocardial infarction, ventricular tachycardias with multiple QRS morphologies typically arise from reentrant circuits within the same infarct region rather than multiple distinct regions.
Cite This Study
Costeas et al. (1997) studied Sustained ventricular tachycardia with multiple QRS morphologies (n=11). Mapping reentrant circuits was evaluated on Mechanisms causing tachycardias with multiple morphologies. In 11 canine hearts with 4-day-old infarcts, tachycardias with multiple QRS morphologies most commonly arose from reentrant circuits in the same region of the infarct with different exit routes.