June 1, 2001Journal of Cardiovascular Electrophysiology

Mechanisms for Spontaneous Changes in QRS Morphology Sometimes Resembling Torsades de Pointes During Reentrant Ventricular Tachycardia in a Canine Infarct Model

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Population

Canine infarct model, 4 days after left anterior descending coronary occlusion (10 tachycardias analyzed)

Design

Preclinical

Authors

HSHeiko SchmittUniversity of Connecticut CCCándido CaboCity University of New York CCConstantinos CosteasNewark Beth Israel Medical Center

Discussion

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Implication

May explain torsades-like QRS changes in stable reentry; hypothesis-generating in animals, human relevance untested.

Structured PICO

Population

Canine infarct model, 4 days after left anterior descending coronary occlusion (10 tachycardias analyzed)

Intervention

Epicardial border zone mapping during sustained ventricular tachycardia

Outcome

Mechanism for spontaneous changes in QRS morphologysurrogate

Subtle changes in conduction velocity within a stable reentrant circuit can shift the exit route, causing QRS morphology changes that may resemble torsades de pointes.

Cite This Study

Schmitt et al. (2001) studied this question.

synapsesocial.com/papers/6a82b289d88fdfcf4fa0c7fd https://doi.org/10.1046/j.1540-8167.2001.00686.x

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Mechanisms for Spontaneous Changes in QRS Morphology Sometimes Resembling Torsades de Pointes During Reentrant Ventricular Tachycardia in a Canine Infarct Model

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Mechanisms for Spontaneous Changes in QRS Morphology Sometimes Resembling Torsades de Pointes During Reentrant Ventricular Tachycardia in a Canine Infarct Model

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Also Consider