What is the clinical evidence from this study?

Study design: Observational. Population: Atrial fibrillation. Primary outcome: Age-standardized death rate (per 100,000) with atrial fibrillation (Average annual increase 5.4%, p=<0.0001).

What question did this study set out to answer?

To evaluate national trends in atrial fibrillation reported as an underlying or contributory cause of death across demographic groups and examine associated comorbidities.

May 1, 2002American Journal of Epidemiology

Increased Atrial Fibrillation Mortality: United States, 1980-1998

Q: What are the key findings of this study?

Atrial fibrillation-related mortality in the United States increased significantly from 27.6 per 100,000 in 1980 to 69.8 per 100,000 in 1998 (average annual increase of 5.4%, p < 0.0001).

Q: What question did this study set out to answer?

To evaluate national trends in atrial fibrillation reported as an underlying or contributory cause of death across demographic groups and examine associated comorbidities.

View Full Paper

Ask AI

Bookmark

Key result

Atrial fibrillation-related mortality in the United States increased significantly from 27.6 per 100,000 in 1980 to 69.8 per 100,000 in 1998 (average annual increase of 5.4%, p < 0.0001).

Population

Decedents in the United States from 1980 through 1998 aged 45 years or older with atrial fibrillation listed…

Design

Cross-sectional

Follow-up

1980 to 1998

Authors

WWWendy A. WattigneyAgency for Toxic Substances and Disease Registry

Discussion

Member takes

Implication

This trend signals a growing public health challenge; leaves open whether post-1998 interventions altered AF mortality.

Key Points

To evaluate national trends in atrial fibrillation reported as an underlying or contributory cause of death across demographic groups and examine associated comorbidities.
Analyzed multiple-cause mortality files from 1980 through 1998 for decedents aged 45 years or older with atrial fibrillation (ICD-9 code 427.3) listed among up to 20 causes of death.
Calculated age-standardized mortality rates and evaluated comorbidity patterns stratified by age, sex, and race (Black vs. White).
Total decedents with atrial fibrillation increased from 18,947 in 1980 to 61,946 in 1998, with the age-standardized death rate rising from 27.6 to 69.8 per 100,000 (average annual increase of 5.4%, p < 0.0001).
The proportion of deaths with atrial fibrillation listed as the primary underlying cause increased from 8.3% to 11.6%, while ischemic heart disease was the most frequent underlying cause overall (26.8%).
Age-standardized mortality rates from 1980 to 1998 were consistently highest in White men, followed by White women, Black men, and Black women.

Study Design

Type

Observational

Structured PICO

Population

Decedents in the United States from 1980 through 1998 aged 45 years or older with atrial fibrillation listed as one of up to 20 conditions causing death.

Outcome

Age-standardized death rates and trends in the reporting of atrial fibrillation as an underlying or contributory cause of death.hard clinical

Main Result

Effect estimate: Average annual increase 5.4%

Absolute Event Rate: 69.8% vs 27.6%

p-value: p=<0.0001

Atrial fibrillation-related mortality increased significantly in the United States between 1980 and 1998, emphasizing the need for improved prevention and control measures.

Cite This Study

Wendy A. Wattigney (2002) conducted an observational in Atrial fibrillation. Atrial fibrillation-related mortality in the United States increased significantly from 27.6 per 100,000 in 1980 to 69.8 per 100,000 in 1998 (average annual increase of 5.4%, p < 0.0001).

synapsesocial.com/papers/6a0f8af14fb650da4ffe3cfa https://doi.org/10.1093/aje/155.9.819

Topics

Atrial fibrillation Persistent AF management Anticoagulation in AF

View Full Paper

Ask AI

Bookmark

Increased Atrial Fibrillation Mortality: United States, 1980-1998

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Topics

Increased Atrial Fibrillation Mortality: United States, 1980-1998

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Also Consider

Topics

Also Consider