Why the study?
Does delaying heparin infusion for 12 hours reduce bleeding without increasing reocclusion in patients receiving intracoronary streptokinase for acute myocardial infarction?
Population
182 patients with acute myocardial infarction treated with intracoronary streptokinase
Comparison
Heparin infused immediately after intracoronary… vs Heparin delayed for 12 hours after intracoronary…
Design
Cohort
Follow-up
at discharge
Authors
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May support delaying heparin to reduce bleeding after streptokinase; leaves open reocclusion effects pending randomized confirmation.
Does delaying heparin infusion for 12 hours reduce bleeding without increasing reocclusion in patients receiving intracoronary streptokinase for acute myocardial infarction?
Delaying heparin for 12 hours after intracoronary streptokinase for acute myocardial infarction may decrease bleeding risk without significantly increasing the risk of reocclusion.
GERALD C. TIMMIS (1986) studied this question.
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