Cigarette smoking, tar yields, and non-fatal myocardial infarction: 14000 cases and 32000 controls in the United Kingdom
Why the study?
Does cigarette smoking and tar yield increase the incidence of non-fatal myocardial infarction in adults?
Population
13,926 survivors of myocardial infarction recently discharged from hospitals in the United Kingdom and…
Comparison
Current smoking of manufactured cigarettes vs Non-smokers
Design
Case-control
Authors
Discussion
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Member takes
Implication
Smoking was associated with fivefold higher MI rates at ages 30-49; leaves open whether low-tar cigarettes meaningfully reduce risk.
Structured PICO
Does cigarette smoking and tar yield increase the incidence of non-fatal myocardial infarction in adults?
P
Population
13,926 survivors of myocardial infarction (cases) recently discharged from hospitals in the United Kingdom and 32,389 of their relatives (controls).
I
Intervention
Current smoking of manufactured cigarettes (low tar < 10 mg or medium tar ≥ 10 mg)
C
Comparator
Non-smokers (had not smoked cigarettes regularly in the past 10 years)
O
Outcome
Incidence of non-fatal myocardial infarctionhard clinical
Smoking significantly increases the risk of non-fatal myocardial infarction across all age groups, and switching to low-tar cigarettes provides minimal benefit compared to smoking cessation.
Cite This Study
Parish et al. (1995) studied this question.