M-mode and two-dimensional echocardiography can reliably assess left ventricular dimensions and ejection fraction in large rats using clinical ultrasound systems, but stroke volume and cardiac output measurements are less reliable.
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Echocardiography reliably measures LV dimensions and EF in rat models; leaves open reliability of stroke volume and cardiac output for translational research.
Wasmeier et al. (2007) studied this question.
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