Key result
Male sex is linked to ~15% higher max-CIMT versus women in healthy young adults.
Why the study?
Early detection of carotid stenosis can reduce cardiovascular risk, motivating the assessment of carotid intima-media thickness, plaque presence, and risk factor correlations in healthy young Thai adults.
Cross-Sectional (n=302)
No
Absolute Event Rate: 0.434% vs 0.377%
p-value: p=<0.05
In healthy young Thai adults, mean and max CIMT are approximately 0.4 mm, with carotid plaque present in nearly 5%, and increased CIMT is associated with male sex, older age, and specific occupations.
Normative CIMT values in young Thai adults should not yet inform screening; extends sparse Asian reference data but leaves longitudinal risk prediction open.
Purpose: Early detection of carotid stenosis can reduce cardiovascular risk.In this study, the maximum-carotid intimamedia thickness (CIMT), the mean-CIMT, and the presence of plaque were examined in healthy young Thai adults.Additionally, correlations between CIMT and cardiovascular risk factors were assessed.Materials and Methods: Left and right carotid arteries of 302 participants (15-45 years old) were scanned, with CIMT measured at the far walls of the common carotid artery, carotid bulb, and internal carotid artery.Demographics and risk factors were assessed using a questionnaire.Ten random participants were re-scanned after 4 weeks. Results:The study included 123 (40.70%) male and 179 (59.30%) female participants.The max-CIMT, mean-CIMT, and plaque thickness were 0.4000.100,0.4030.095and 1.5200.814mm, respectively.Male participants had significantly higher CIMT values for nearly all locations and age groups.The right-sided CIMT values were higher for all locations.The carotid bulb had the greatest CIMT values (0.4370.178 mm), followed by the common (0.4030.095 mm) and internal (0.3610.099 mm) carotid arteries.Plaque was present in 18 locations (1.00%), affecting 15 participants (4.97%).These plaques were found in the right carotid bulb (n = 9; 0.50%), left carotid bulb (n = 7; 0.39%), and right internal carotid artery (n = 2; 0.11%).Adjusted multivariable regression revealed significant positive associations between CIMT and male, increased age and "other" occupation (P<0.05).Conclusion: Both max-CIMT and mean-CIMT were approximately 0.4 mm.Plaque was observed in 4.97% of patients, with an average thickness of 1.5 mm.The most influential risk factors for increased CIMT were sex, age, and occupation.
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Panprasit et al. (2023) conducted a cross-sectional in Healthy (n=302). Male sex vs. Female sex was evaluated on Maximum carotid intima-media thickness (max-CIMT) in mm (p=<0.05). In healthy young Thai adults, maximum carotid intima-media thickness was significantly higher in men (0.434 mm) than in women (0.377 mm), and was positively associated with age and occupation.
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