Key result
Hypertension was the strongest risk factor for increased carotid intima-media thickness, whereas coronary artery disease (OR 3.14) and dyslipidemia (OR 1.84) significantly increased the probability of carotid plaque.
Why the study?
Do traditional cardiovascular risk factors differentially affect carotid intima-media thickness and carotid plaque occurrence in outpatients?
Population
553 outpatients who underwent a carotid artery ultrasound
Design
Cross-sectional
Authors
Loading...
May guide sex-specific CIMT interpretation in outpatients; leaves open differential effects of risk factors on progression.
Cross-Sectional (n=553)
No
Do traditional cardiovascular risk factors differentially affect carotid intima-media thickness and carotid plaque occurrence in outpatients?
Odds Ratio: 3.14 (95% CI 1.76–5.62)
Absolute Event Rate: 42.25% vs 21.07%
p-value: p=<0.001
Hypertension primarily increases carotid intima-media thickness, whereas age and dyslipidemia are more strongly associated with carotid plaque occurrence, suggesting different adaptive responses to risk factors.
Baroncini et al. (2015) conducted a cross-sectional in Cardiovascular risk factors (hypertension, diabetes, dyslipidemia, smoking, CAD) (n=553). Coronary artery disease (CAD) vs. Patients without coronary artery disease was evaluated on Probability of carotid plaque occurrence (OR 3.14, 95% CI 1.76-5.62, p=<0.001). Hypertension was the strongest risk factor for increased carotid intima-media thickness, whereas coronary artery disease (OR 3.14) and dyslipidemia (OR 1.84) significantly increased the probability of carotid plaque.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: