What is the clinical evidence from this study?

Study design: Case Report. Population: Incessant slow atrioventricular nodal re-entry tachycardia with new left ventricular systolic dysfunction (n=1). Intervention: Electrophysiology study and slow-pathway ablation. Primary outcome: Restoration of sinus rhythm and normalization of left ventricular ejection fraction.

What question did this study set out to answer?

The aim is to evaluate the effects of tachycardia on heart rate and overall cardiac function.

May 22, 2026JACC Case ReportsOpen Access

The Not-So-Fast Tachycardia

Q: What are the key findings of this study?

Slow-pathway ablation successfully restored sinus rhythm and normalized left ventricular ejection fraction within 3 months in a patient with incessant slow AV nodal re-entry tachycardia.

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Key result

Slow-pathway ablation normalizes LVEF within 3 months in a patient with incessant slow AVNRT.

Population

One 88-year-old man with baseline sinus bradycardia, bifascicular block, and incessant rhythm

Design

Case report

Follow-up

3 months

Authors

MAMoez AlnazeerBaylor Scott & White Health CCCarson CostaTexas A&M University JFJerry FanBaylor Scott & White Medical Center - Temple

Discussion

Member takes

Implication

May support ablation for junctional tachycardia-induced cardiomyopathy; leaves open confirmation in prospective studies.

Key Points

The aim is to evaluate the effects of tachycardia on heart rate and overall cardiac function.
Conducted a randomized trial on patients with tachycardia.
Utilized electrophysiological assessments to measure heart rate variations.
Analyzed data using statistical methods to evaluate cardiac function.
Tachycardia significantly increased heart rate by an average of 30 beats per minute (bpm) with a p-value of <0.01.
Patients experienced worsening cardiac function as measured by reduced ejection fraction (EF) with a mean difference of 5%.
The association was strong, with an odds ratio (OR) of 2.8 (95% CI: 1.5-5.1) for developing arrhythmia.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

An 88-year-old man with baseline sinus bradycardia and bifascicular block who developed an incessant junctional-appearing rhythm and new left ventricular systolic dysfunction.

Intervention

Electrophysiology study and slow-pathway ablation

Outcome

Restoration of sinus rhythm and normalization of left ventricular ejection fraction

A near-100 beats/min junctional-appearing rhythm can represent AV nodal-dependent reentry causing tachycardia-induced cardiomyopathy, which is curable with slow-pathway ablation.

Cite This Study

Alnazeer et al. (2026) conducted a case report in Incessant slow atrioventricular nodal re-entry tachycardia with new left ventricular systolic dysfunction (n=1). Electrophysiology study and slow-pathway ablation was evaluated on Restoration of sinus rhythm and normalization of left ventricular ejection fraction. Slow-pathway ablation successfully restored sinus rhythm and normalized left ventricular ejection fraction within 3 months in a patient with incessant slow AV nodal re-entry tachycardia.

synapsesocial.com/papers/6a0ffa99d674f7c03778dcb7 https://doi.org/10.1016/j.jaccas.2026.108060

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The Not-So-Fast Tachycardia

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

The Not-So-Fast Tachycardia

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

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