Key result
CPAP improves HRV in OSA by decreasing sympathovagal balance and increasing vagal tone.
Why the study?
Patients with obstructive sleep apnea often exhibit autonomic alterations observed via heart rate variability, but the effects of medium- and long-term continuous positive airway pressure therapy on these changes needed evaluation.
Does CPAP therapy change heart rate variability in patients with obstructive sleep apnea?
Does CPAP therapy change heart rate variability in patients with obstructive sleep apnea?
CPAP therapy for at least one month alters heart rate variability in patients with obstructive sleep apnea, suggesting an impact on autonomic dysfunction.
CPAP may improve autonomic balance in OSA; confirms consistent HRV benefits and supports trials on CV outcomes.
INTRODUCTION: Obstructive sleep apnea (OSA) is a respiratory sleep disorder. Many of these patients also exhibit autonomic alterations which can be observed through heart rate variability (HRV). Currently, one of the treatments for apnea is continuous positive airway pressure (CPAP). OBJECTIVE: To observe OSA patients treated with CPAP exhibit HRV changes at medium and long treatment period. METHODS: This is an integrative literature review conducted in May of 2018. The databases used for this research were PubMed, Scopus, Scielo and Pedro, the keywords used were "heart rate variability", "obstructive sleep apnea" and "CPAP". In this review was included original, published, randomized and non-randomized articles, released in the English language, before and up to April 2018, which specified the effects of CPAP therapy in autonomic dysfunction through the analysis of the HRV of patients diagnosed with OSA after at least one month of therapy. RESULTS: The research of the literature produced 113 articles. After excluding duplicates and applying the inclusion and exclusion criteria, 8 articles were selected for this review. CONCLUSION: It was concluded that CPAP therapy is related to change in heart rate variability in patients with obstructive sleep apnea.
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Correia et al. (2019) conducted a review in Obstructive sleep apnea (OSA) (n=186). Continuous positive airway pressure (CPAP) vs. Baseline (pre-therapy) or control group was evaluated on Heart rate variability (HRV) parameters (LF, HF, LF/HF, SDNN, pNN50). Continuous positive airway pressure therapy alters heart rate variability in patients with obstructive sleep apnea, significantly decreasing sympathovagal balance and increasing the vagal component.
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