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November 1, 2002The Journal of Clinical Endocrinology & Metabolism

Abdominal Obesity, Muscle Composition, and Insulin Resistance in Premenopausal Women

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Why the study?

Does visceral adipose tissue mass correlate with insulin resistance in abdominally obese premenopausal women?

Population

40 abdominally obese, premenopausal women

Design

Cross-sectional

Authors

RRRobert RossJFJennifer FreemanRHRobert Hudson

Discussion

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Overview

Visceral AT mass was independently associated with insulin resistance; leaves open causality and need for prospective intervention trials.

Structured PICO

Does visceral adipose tissue mass correlate with insulin resistance in abdominally obese premenopausal women?

P
Population
40 abdominally obese, premenopausal women
O
Outcome
Glucose disposal rate (insulin sensitivity) measured by euglycemic clampsurrogate

Visceral adipose tissue is a strong, independent correlate of insulin resistance in abdominally obese premenopausal women, whereas subcutaneous adipose tissue and muscle composition are not.

Cite This Study

Ross et al. (2002) studied this question.

synapsesocial.com/papers/6a10191e01be78fe81606a97https://doi.org/10.1210/jc.2002-020570
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