Why the study?
Do diabetes and pre-diabetic metabolic impairments accelerate the decline in heart rate variability over time in adults aged 45-64 years?
Population
Population-based cohort of 6,245 individuals aged 45-64 years at baseline for longitudinal analysis, and…
Comparison
Diabetes and pre-diabetic metabolic impairments vs Nondiabetic subjects with normal fasting glucose
Design
Cohort
Follow-up
9 years
Authors
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May warrant autonomic monitoring in diabetes; extends longitudinal observations but leaves causal interventions open.
Do diabetes and pre-diabetic metabolic impairments accelerate the decline in heart rate variability over time in adults aged 45-64 years?
Diabetes is associated with a more rapid progressive worsening of cardiac autonomic function, as measured by heart rate variability, over a 9-year period compared to nondiabetic individuals.
Schroeder et al. (2005) studied this question.
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