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October 1, 2017Revista Portuguesa de CardiologiaOpen Access

The percentages of clinical and echocardiographic responders were similar in the two groups, but there were more functional responders in the AF group (71% vs. 39% in SR patients; p=0.012).

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Why the study?

Does permanent atrial fibrillation modify response to cardiac resynchronization therapy in heart failure patients?

Population

101 heart failure patients treated by cardiac resynchronization therapy, divided into atrial fibrillation…

Comparison

Cardiac resynchronization therapy in patients… vs Cardiac resynchronization therapy in patients…

Design

Cohort

Follow-up

6 months

Authors

AAAna AbreuMOMário OliveiraPCPedro Silva Cunha

Discussion

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Overview

Supports CRT consideration in HF with permanent AF; leaves open confirmation of differential functional response in randomized trials.

Structured PICO

Does permanent atrial fibrillation modify response to cardiac resynchronization therapy in heart failure patients?

P
Population
101 heart failure patients treated by cardiac resynchronization therapy (CRT), divided into atrial fibrillation (AF, n=35) and sinus rhythm (SR, n=66) groups.
I
Intervention
Cardiac resynchronization therapy (CRT) in patients with atrial fibrillation (AF)
C
Comparator
Cardiac resynchronization therapy (CRT) in patients with sinus rhythm (SR)
O
Outcome
Rates of clinical, echocardiographic and functional response at three and six months after implantationsurrogate

Cardiac resynchronization therapy provides similar clinical and echocardiographic benefits in heart failure patients with atrial fibrillation compared to those in sinus rhythm, with potentially greater functional improvements in the AF group.

Cite This Study

Abreu et al. (2017) studied this question.

synapsesocial.com/papers/6a101e214fb650da4ffef86fhttps://doi.org/10.1016/j.repc.2017.02.016
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Outcomes of cardiac resynchronization therapy in patients with atrial fibrillation accompanied by slow ventricular response2019 · 8 citations
  2. 2Long-term effects of cardiac resynchronisation therapy in patients with atrial fibrillation2008 · 123 citations
  3. 3Does permanent atrial fibrillation modify response to cardiac resynchronization therapy in heart failure patients?2017
  4. 4Cardiac Resynchronization Therapy Defibrillators in Patients with Permanent Atrial Fibrillation2021 · 5 citations
  5. 5Cardiac resynchronisation therapy in chronic atrial fibrillation: impact on left atrial size and reversal to sinus rhythm2005 · 71 citations