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April 1, 1982Circulation Research255 citationsOpen Access

Increased myothermal economy of isometric force generation in compensated cardiac hypertrophy induced by pulmonary artery constriction in the rabbit. A characterization of heat liberation in normal and hypertrophied right ventricular papillary muscles.

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NANorman R. AlpertUniversity of VermontLML. A. MulieriUniversity of Vermont

Key Points

  • This research aims to characterize heat liberation in normal versus hypertrophied right ventricular papillary muscles during isometric force generation.
  • Analyzed heat production in rabbit papillary muscles under isometric conditions.

Structured PICO

P
Population
Rabbit right ventricular papillary muscles (normal and hypertrophied induced by pulmonary artery constriction)
I
Intervention
Pulmonary artery constriction to induce compensated cardiac hypertrophy
C
Comparator
Normal right ventricular papillary muscles (controls)
O
Outcome
Heat liberation (myothermal economy of isometric force generation)surrogate

This study provides updated baseline values for rabbit papillary muscle energetics based on a larger sample size.

Abstract

because the controls in the earlier series of five muscles liberated 40% more initial heat per gram of muscle than did the present controls. We believe the present values, obtained from a much larger population, to be a better representation of rabbit papillary muscle energetics.

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Cite This Study

Alpert et al. (1982) studied this question.

synapsesocial.com/papers/6a1039e892676d5461fdc07bhttps://doi.org/10.1161/01.res.50.4.491
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