Why the study?
Does converting enzyme inhibition alter blood pressure and hemodynamics in normotensive subjects?
Population
14 normal (normotensive) human subjects
Comparison
Converting enzyme inhibitor administered during… vs Baseline measurements prior to converting enzyme…
Design
Other
Authors
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ACEI lowers BP in normotensives on normal sodium; extends RAS role in regulation but leaves open clinical relevance.
Does converting enzyme inhibition alter blood pressure and hemodynamics in normotensive subjects?
The renin-angiotensin system actively participates in blood pressure and cardiovascular regulation in normotensive subjects, even during normal sodium intake.
Niarchos et al. (1979) studied this question.
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