What does this research mean for the field?

A newly devised cannula with bipolar electrodes can successfully produce permanent atrioventricular (AV) block in animal models through targeted injection of anhydrous alcohol guided by His bundle electrograms. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 1985The Tohoku Journal of Experimental MedicineOpen Access

A simple catheter technique for production of AV block.

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Population

10 dogs weighing 6.0 to 12.0 kg

Design

Preclinical

Follow-up

3 weeks

Authors

YAYoshifusa AizawaElectrophysiology YTYoshimatsu TamuraNiigata University MMMinoru MurataSaitama Institute of Technology

Discussion

Member takes

Implication

Supports feasibility of catheter alcohol ablation in canines; hypothesis-generating for human use, no practice change yet.

Structured PICO

Population

10 dogs weighing 6.0 to 12.0 kg

Intervention

Catheter-guided subendocardial injection of 0.2 ml lidocaine hydrochloride (Xylocain) mixed with contrast material, followed by 0.2 to 0.4 ml of anhydrous alcohol into the AV nodal region

Outcome

Production of permanent AV block

A novel catheter technique using bipolar electrodes to guide the injection of anhydrous alcohol successfully produced permanent AV block in a canine model, suggesting potential feasibility for human application without general anesthesia.

Limitations

Inability to make AV block in some dogs due to a failure to access the His bundle because of difficulty in manipulating the catheter in small dogs

Cite This Study

Aizawa et al. (1985) studied this question.

synapsesocial.com/papers/6a10d1835e6663f9d2647ba2 https://doi.org/10.1620/tjem.147.177

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Bookmark

A simple catheter technique for production of AV block.

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

A simple catheter technique for production of AV block.

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

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