What does this research mean for the field?

A novel injection device providing real-time electrocardiogram guidance and physical depth restriction during right thoracotomy in rabbits effectively induces chronic atrioventricular block and reproduces the surgical pathology of congenital heart surgery. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 15, 2010Brazilian Journal of Medical and Biological ResearchOpen Access

An improved in vivo method for atrioventricular node ablation via thoracotomy

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Why the study?

Does ECG guidance during formalin injection improve the induction of chronic AV block in an adult rabbit model?

Population

Adult rabbits

Comparison

Atrioventricular node ablation via right… vs AV node ablation without ECG guidance

Design

Preclinical

Follow-up

>12 h

Authors

RMRobroy MacIverChildren’s Minnesota - St. Paul Hospital RSRobert D. StewartUniversity of Washington CBChristina BäckerJustus-Liebig-Universität Gießen

Discussion

Member takes

Implication

May refine rabbit AV block models; leaves open translation to larger animals or humans.

Structured PICO

Does ECG guidance during formalin injection improve the induction of chronic AV block in an adult rabbit model?

Population

Adult rabbits

Intervention

Atrioventricular (AV) node ablation via right thoracotomy using a novel injection device with ECG guidance and formalin injection

Comparator

AV node ablation without ECG guidance

Outcome

Induction and maintenance of chronic AV block (>12 h)

A novel ECG-guided injection device improves the reliability of inducing chronic complete heart block in a rabbit model via thoracotomy.

Cite This Study

MacIver et al. (2010) studied this question.

synapsesocial.com/papers/6a1d4670164c88e7165dd7da https://doi.org/10.1590/s0100-879x2010005000003

Topics

AF ablation outcomes

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An improved in vivo method for atrioventricular node ablation via thoracotomy

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

An improved in vivo method for atrioventricular node ablation via thoracotomy

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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