The Triage-HF Plus clinical pathway combining CIED risk-stratification and telephone triage identified worsening heart failure with 98.6% sensitivity and 63.4% specificity.
Observational (n=255)
No
Does the Triage-HF Plus clinical pathway accurately identify worsening heart failure in patients with heart failure and in situ CIEDs?
The Triage-HF Plus pathway, combining CIED-derived risk stratification with telephone triage, demonstrates high sensitivity for identifying worsening heart failure events.
Effect estimate: Sensitivity 98.6%, Specificity 63.4% (95% CI 92.5-100.0 (Sensitivity), 55.2-71.0 (Specificity))
Absolute Event Rate: 55.9% vs 1%
AIMS: Remote monitoring of patients with physiological data derived from cardiac implanted electronic devices (CIEDs) offers potential to reconfigure clinical services. The 'Heart Failure Risk Score' (HFRS) uses input from integrated device physiological monitoring to risk-stratify patients as low-risk, medium-risk, or high-risk of a heart failure event in the next 30 days. This study aimed to evaluate a novel clinical pathway utilizing a combination of CIED risk-stratification and telephone triage to identify patients with worsening heart failure (WHF). METHODS AND RESULTS: A prospective, single-centre, real-world evaluation of the 'Triage-HF Plus' clinical pathway (HFRS in combination with telephone triage) over a 27 month period. One hundred and fifty-seven high-risk HFRS transmissions were referred for telephone triage assessment. Interventions were at the discretion of the clinical assessor acting in accordance with clinical guidelines. An additional 3month consecutive sample of low and medium HFRS transmissions (control group) were also contacted for telephone triage assessment (n = 98). Successful telephone contact was made in 127 (81%) of referred high-risk HFRS cases: 71 (55.9%) were confirmed to have WHF requiring intervention; 19 (14.9%) had an alternative acute medical problem; one patient had been recently discharged from hospital with WHF; and 36 (28.0%) had no apparent cause for the high score. In the control group, only one patient had symptoms of WHF. The sensitivity and specificity of CIED-based remote monitoring to identify WHF 98.6% (92.5-100.0%) and 63.4% (55.2-71.0%), respectively. CONCLUSIONS: The Triage-HF Plus clinical pathway is a potentially useful remote monitoring tool for patients with heart failure and in situ CIEDs.
Ahmed et al. (Tue,) conducted a observational in Heart failure (n=255). Triage-HF Plus clinical pathway vs. Low and medium HFRS transmissions was evaluated on Identification of worsening heart failure (WHF) (Sensitivity 98.6%, Specificity 63.4%, 95% CI 92.5-100.0 (Sensitivity), 55.2-71.0 (Specificity)). The Triage-HF Plus clinical pathway combining CIED risk-stratification and telephone triage identified worsening heart failure with 98.6% sensitivity and 63.4% specificity.