Key result
Systemic inflammation and RAAS hyperactivation act as shared pathogenic links between atherosclerosis and depressive disorders.
Why the study?
This literature review aims to explore novel cardiovascular risk factors that complement classic risk factors, focusing on the link between depressive disorders and cardiovascular diseases.
Answers are grounded in this paper and cite their sources.
Shared pathogenetic pathways between atherosclerosis and depression, such as systemic inflammation and RAAS hyperactivation, may offer new therapeutic strategies.
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Смирнова et al. (2021) conducted a review in Atherosclerosis and depression. Chronic systemic inflammation and hyperactivation of the renin-angiotensin-aldosterone system serve as common pathogenetic links between atherosclerosis and depressive disorders.
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