November 23, 1998
Depression and risk of coronary heart disease in elderly men and women: New Haven EPESE, 1982-1991. Established Populations for the Epidemiologic Studies of the Elderly.
Why the study?
Do depressive symptoms predict incident coronary heart disease in elderly men and women?
Population
Elderly men and women from the New Haven, Conn, cohort of the Established Populations for the Epidemiologic…
Comparison
Depressive symptoms (measured at baseline in 1982) vs Lower or no depressive symptoms
Design
Cohort
Follow-up
9 years (1982-1991)
Authors
Discussion
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Member takes
Implication
May inform sex-stratified CHD risk models in older women; leaves open causality and need for prospective validation.
Structured PICO
Do depressive symptoms predict incident coronary heart disease in elderly men and women?
P
Population
Elderly men and women from the New Haven, Conn, cohort of the Established Populations for the Epidemiologic Studies of the Elderly project (N = 2812)
I
Intervention
Depressive symptoms (measured at baseline in 1982)
C
Comparator
Lower or no depressive symptoms
O
Outcome
CHD deaths and total incident CHD events (nonfatal myocardial infarctions and CHD deaths) between January 1, 1982, and December 31, 1991hard clinical
Depressive symptoms may increase the risk of coronary heart disease outcomes in relatively healthy older women, but not in older men or the general elderly population with physical impairments.
Cite This Study
Leon et al. (1998) studied this question.